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.coreshangye-download-button{flex:0 0 auto;margin:0;padding:8px 10px}}<\/p>\n<p>.coreshangye-body .coreshangye-sidebar{--coreshangye-muted:#526571}\n.coreshangye-body .coreshangye-content{min-width:0}\n.coreshangye-body .coreshangye-solution-layout{padding-bottom:52px}\n@media(max-width:760px){.coreshangye-body .coreshangye-sidebar{min-width:0}.coreshangye-body .coreshangye-sidebar nav{flex-shrink:0}}<\/p>\n<p>.coreshangye-body .coreshangye-no-image{grid-template-columns:1fr}.coreshangye-body .coreshangye-hero-description p:last-child{margin-bottom:0}<\/style>\n<p><script type=\"application\/ld+json\">{\n \"@context\": \"https:\\\/\\\/schema.org\",\n \"@type\": \"FAQPage\",\n \"mainEntity\": [\n {\n \"@type\": \"Question\",\n \"name\": \"Is the ingredient sourced from human milk?\",\n \"acceptedAnswer\": {\n \"@type\": \"Answer\",\n \"text\": \"The manufacturing source is not stated in the general product information. Sgnutri can provide the source and process information for the specific product offered.\"\n }\n },\n {\n \"@type\": \"Question\",\n \"name\": \"Can one HMO replace another at the same use level?\",\n \"acceptedAnswer\": {\n \"@type\": \"Answer\",\n \"text\": \"Not by default. Linkage pattern, purity, related sugars, stability, supporting evidence, and permitted conditions of use can differ. A valid substitution must satisfy the finished-product specification, use level, evidence, and target-market requirements.\"\n }\n }\n ]\n}<\/script><script type=\"application\/ld+json\">{\n \"@context\": \"https:\\\/\\\/schema.org\",\n \"@type\": \"ItemList\",\n \"numberOfItems\": 1,\n \"itemListElement\": [\n {\n \"@type\": \"ListItem\",\n \"position\": 1,\n \"name\": \"Human milk oligosaccharides (HMOs)\",\n \"url\": \"https:\\\/\\\/www.sgnutri.com\\\/human-milk-oligosaccharides-hmos\\\/\"\n }\n ]\n}<\/script><\/head><body><main class=\"coreshangye-body\"><\/p>\n<header class=\"coreshangye-hero\" id=\"coreshangye-top\">\n<div class=\"coreshangye-hero-media\" aria-hidden=\"true\"><\/div>\n<div class=\"coreshangye-shell coreshangye-hero-inner coreshangye-no-image\">\n<div class=\"coreshangye-hero-content\">\n<nav class=\"coreshangye-breadcrumbs\" aria-label=\"Percorso di navigazione\"><a href=\"https:\/\/www.sgnutri.com\/it\/\">Casa<\/a><span aria-hidden=\"true\">\/<\/span><a href=\"https:\/\/www.sgnutri.com\/it\/categoria\/tutti-i-prodotti\/\">Prodotti<\/a><span aria-hidden=\"true\">\/<\/span><span>human milk oligosaccharide<\/span><\/nav>\n<h1>human milk oligosaccharide<\/h1>\n<div class=\"coreshangye-hero-description\">\n<p>Human milk oligosaccharides (HMOs) are a structurally diverse family of complex carbohydrates. Their identity determines molecular properties, analytical specifications, scientific evidence, and permitted conditions of use. Explore the available Sgnutri product, compare the information needed for formulation, and request documents for your target market.<\/p>\n<\/div>\n<div class=\"coreshangye-actions\"><a class=\"coreshangye-button coreshangye-button-primary\" href=\"#hmo-products\">Explore the HMO Product<\/a><a class=\"coreshangye-button coreshangye-button-ghost\" href=\"#coreshangye-quote\" data-product=\"Human milk oligosaccharides (HMOs)\">Request Product Information<\/a><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/header>\n<div class=\"coreshangye-shell coreshangye-solution-layout\">\n<aside class=\"coreshangye-sidebar\" aria-label=\"Page contents\">\n<h2>In questa pagina<\/h2>\n<nav aria-label=\"On this page\"><a href=\"#hmo-structure\">What a human milk oligosaccharide is<\/a><a href=\"#functional-relevance\">Structure determines functional relevance<\/a><a href=\"#hmo-products\">Explore Sgnutri's HMO ingredient<\/a><a href=\"#two-fl-specification\">2'-FL\/HMO specification, quality, and handling<\/a><a href=\"#hmo-selection\">Choose an HMO by structure, evidence, and end use<\/a><a href=\"#hmo-faq\">Frequently asked questions<\/a><a href=\"#coreshangye-quote\">Request Human Milk Oligosaccharide Information<\/a><\/nav>\n<\/aside>\n<div class=\"coreshangye-content\">\n<section class=\"coreshangye-keyword-module palette-0\" id=\"hmo-structure\" aria-labelledby=\"hmo-structure-title\">\n<div class=\"wrap\">\n<h2 id=\"hmo-structure-title\">What a human milk oligosaccharide is<\/h2>\n<p>HMOs share a lactose unit at the reducing end, but extensions and the addition of fucose or sialic acid create many distinct molecules. More than 200 HMO structures have been described in human milk. \u201cHMO\u201d therefore identifies a family; it does not provide a complete chemical identity for purchasing or formulation.<\/p>\n<div class=\"scroll\" tabindex=\"0\" role=\"region\" aria-label=\"Scrollable table\">\n<table>\n<thead>\n<tr>\n<th>Structural group<\/th>\n<th>Representative examples<\/th>\n<th>Why the distinction matters<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Neutral fucosylated HMOs<\/td>\n<td>2′-fucosyllactose (2′-FL), 3-fucosyllactose (3-FL)<\/td>\n<td>The position and linkage of fucose distinguish individual molecules and their analytical profiles.<\/td>\n<\/tr>\n<tr>\n<td>Neutral non-fucosylated HMOs<\/td>\n<td>Lacto-N-tetraose (LNT), lacto-N-neotetraose (LNnT)<\/td>\n<td>LNT and LNnT have different linkages, so one cannot substitute for the other on name alone.<\/td>\n<\/tr>\n<tr>\n<td>Acidic, sialylated HMOs<\/td>\n<td>3′-sialyllactose (3′-SL), 6′-sialyllactose (6′-SL)<\/td>\n<td>Sialic acid gives these HMOs acidic character; linkage position again defines the specific ingredient.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>A commercial specification should name the exact HMO or defined mixture. That identity determines the formula, molecular weight, CAS information where applicable, assay method, impurity profile, and regulatory review.<\/p>\n<\/div>\n<\/section>\n<section class=\"coreshangye-keyword-module palette-1\" id=\"functional-relevance\" aria-labelledby=\"functional-relevance-title\">\n<div class=\"wrap\">\n<h2 id=\"functional-relevance-title\">Structure determines functional relevance<\/h2>\n<p>HMO research describes several complementary biological pathways, and each depends on molecular structure. Some HMOs are selectively used by particular gut microorganisms, including certain <em>Bifidobacterium<\/em> strains. This selective use can influence microbial ecology and the metabolites produced during fermentation.<\/p>\n<p>Some HMO structures can also interact with microbial adhesion targets as soluble decoys. The relevant binding behavior depends on the terminal sugars and linkages present, so evidence for one HMO cannot be transferred automatically to another.<\/p>\n<p>Research also examines interactions between HMOs, intestinal epithelial processes, and immune signaling. Evidence remains structure-specific: a result associated with one molecule, dose, or population does not establish the same result for the entire HMO family.<\/p>\n<\/div>\n<\/section>\n<section class=\"coreshangye-keyword-module palette-2\" id=\"hmo-products\" aria-labelledby=\"hmo-products-title\">\n<div class=\"wrap\">\n<h2 id=\"hmo-products-title\">Explore Sgnutri's HMO ingredient<\/h2>\n<div class=\"coreshangye-product-grid coreshangye-products-single\">\n<article class=\"coreshangye-solution-card\"><a class=\"coreshangye-product-media\" href=\"https:\/\/www.sgnutri.com\/it\/oligosaccaridi-del-latte-umano-hmos\/\" aria-label=\"View Human milk oligosaccharides (HMOs)\"><img src=\"https:\/\/www.sgnutri.com\/wp-content\/uploads\/2025\/01\/pro1-1.png\" alt=\"White human milk oligosaccharide powder in a brown bowl on a white background.\" width=\"800\" height=\"800\" loading=\"lazy\" decoding=\"async\"><\/a><\/p>\n<div class=\"coreshangye-product-body\">\n<h3><a href=\"https:\/\/www.sgnutri.com\/it\/oligosaccaridi-del-latte-umano-hmos\/\">Human milk oligosaccharides (HMOs)<\/a><\/h3>\n<p>A white to off-white powder or crystalline ingredient listing for buyers evaluating HMOs. Because HMOs are a group of structurally distinct compounds, the exact identity and product-specific specification should be confirmed with the quotation.<\/p>\n<ul class=\"coreshangye-metric-list\">\n<li><span>Formula chimica<\/span><strong>Varies by HMO structure<\/strong><\/li>\n<li><span>Numero CAS<\/span><strong>No single CAS number applies to the HMO group<\/strong><\/li>\n<li><span>Peso molecolare<\/span><strong>Varies by oligosaccharide<\/strong><\/li>\n<li><span>Aspetto<\/span><strong>Polvere o forma cristallina di colore da bianco a biancastro<\/strong><\/li>\n<li><span>Thermal behavior<\/span><strong>Si decompone prima della fusione<\/strong><\/li>\n<\/ul>\n<div class=\"coreshangye-card-actions\"><a class=\"coreshangye-button coreshangye-button-primary\" href=\"#coreshangye-quote\" data-product=\"Human milk oligosaccharides (HMOs)\" data-inquiry-text=\"I am interested in Human milk oligosaccharides (HMOs). Please send product information, sample availability, and a quotation.\">Ask About This HMO<\/a><a class=\"coreshangye-button coreshangye-button-light\" href=\"https:\/\/www.sgnutri.com\/it\/oligosaccaridi-del-latte-umano-hmos\/\">View Product Details<\/a><\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"coreshangye-keyword-module palette-3\" id=\"two-fl-specification\" aria-labelledby=\"two-fl-specification-title\">\n<div class=\"wrap\">\n<h2 id=\"two-fl-specification-title\">2'-FL\/HMO specification, quality, and handling<\/h2>\n<p>The reference specification supplied for 2′-fucosyllactose (2′-FL\/HMO) lists the following composition and quality limits. These values describe the supplied 2′-FL\/HMO specification; they are not a universal specification for every HMO structure.<\/p>\n<h3>Composition and physical criteria<\/h3>\n<div class=\"scroll\" tabindex=\"0\" role=\"region\" aria-label=\"Scrollable table\">\n<table>\n<thead>\n<tr>\n<th>Test<\/th>\n<th>Reference specification<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Aspetto<\/td>\n<td>Polvere bianca<\/td>\n<\/tr>\n<tr>\n<td>2′-FL<\/td>\n<td>\u226594.0% w\/w<\/td>\n<\/tr>\n<tr>\n<td>Umidit\u00e0<\/td>\n<td>\u22649.0% w\/w<\/td>\n<\/tr>\n<tr>\n<td>D-lactose<\/td>\n<td>\u22643.0% w\/w<\/td>\n<\/tr>\n<tr>\n<td>Difucosyl lactose<\/td>\n<td>\u22642.0% w\/w<\/td>\n<\/tr>\n<tr>\n<td>Proteine<\/td>\n<td>\u2264100 mg\/kg<\/td>\n<\/tr>\n<tr>\n<td>Cenere<\/td>\n<td>\u22640.5% w\/w<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h3>Contaminant and microbiological criteria<\/h3>\n<div class=\"scroll\" tabindex=\"0\" role=\"region\" aria-label=\"Scrollable table\">\n<table>\n<thead>\n<tr>\n<th>Test<\/th>\n<th>Reference specification<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Endotoxin<\/td>\n<td>\u226410 EU\/mg<\/td>\n<\/tr>\n<tr>\n<td>Arsenico (As)<\/td>\n<td>\u22640.2 mg\/kg<\/td>\n<\/tr>\n<tr>\n<td>Piombo (Pb)<\/td>\n<td>\u22640.05 mg\/kg<\/td>\n<\/tr>\n<tr>\n<td>Conteggio totale delle piastre<\/td>\n<td>\u2264500 CFU\/g<\/td>\n<\/tr>\n<tr>\n<td>Coliformi<\/td>\n<td><10 CFU\/g<\/td>\n<\/tr>\n<tr>\n<td><em>Salmonella<\/em><\/td>\n<td>Negative in 25 g<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>This 2′-FL\/HMO is packed in 20 kg (44.1 lb) food-grade aluminum-foil composite bags. Its stated shelf life is 24 months under dry, clean, and ventilated storage conditions. Keep the bag closed and protect the powder from moisture during warehousing and sampling.<\/p>\n<p>The current technical data sheet and batch certificate of analysis provide the applicable release criteria and results for an order.<\/p>\n<p><a class=\"button\" href=\"#coreshangye-quote\" data-product=\"Human milk oligosaccharides (HMOs)\">Request the Current Specification<\/a><\/div>\n<\/section>\n<section class=\"coreshangye-keyword-module palette-0\" id=\"hmo-selection\" aria-labelledby=\"hmo-selection-title\">\n<div class=\"wrap\">\n<h2 id=\"hmo-selection-title\">Choose an HMO by structure, evidence, and end use<\/h2>\n<p>The intended function narrows the relevant evidence, but the molecule named in that evidence still controls the ingredient choice. A study on 2′-FL, for example, does not establish an equivalent outcome for LNnT or a sialylated HMO. Consumer group, serving level, and final product format further determine whether that evidence fits a formulation.<\/p>\n<p>Commercial ingredients with the same HMO name are not automatically interchangeable. Manufacturing process, purity, related sugars, microbiological limits, and stability can affect regulatory support, processing behavior, analytical release, and label review. A substitute should therefore be assessed against the finished-product specification and substantiation, not only the name on a catalog page.<\/p>\n<p>In the United States, safety and regulatory support is tied to the specific substance, manufacturing description, specifications, food categories, use levels, and population described in the supporting record. Infant formula, foods for young children, dietary supplements, and general foods do not share one universal use framework. The FDA’s <a href=\"https:\/\/www.fda.gov\/food\/generally-recognized-safe-gras\/gras-notice-inventory\" rel=\"nofollow noopener\" target=\"_blank\">GRAS Notice Inventory<\/a> is a useful starting point for reviewing these conditions; a notice concerning another source or process does not automatically cover a quoted ingredient.<\/p>\n<p>Ask Sgnutri to match the offered HMO and its technical documentation to the final product, consumer group, target use level, and market before a formulation is locked.<\/p>\n<p><a class=\"button\" href=\"#coreshangye-quote\" data-product=\"Human milk oligosaccharides (HMOs)\">Discuss Your U.S. Application<\/a><\/div>\n<\/section>\n<section class=\"coreshangye-keyword-module palette-1\" id=\"hmo-faq\" aria-labelledby=\"hmo-faq-title\">\n<div class=\"wrap\">\n<h2 id=\"hmo-faq-title\">Frequently asked questions<\/h2>\n<details>\n<summary>Is the ingredient sourced from human milk?<\/summary>\n<p>The manufacturing source is not stated in the general product information. Sgnutri can provide the source and process information for the specific product offered.<\/p>\n<\/details>\n<details>\n<summary>Can one HMO replace another at the same use level?<\/summary>\n<p>Not by default. Linkage pattern, purity, related sugars, stability, supporting evidence, and permitted conditions of use can differ. A valid substitution must satisfy the finished-product specification, use level, evidence, and target-market requirements.<\/p>\n<\/details>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<section class=\"coreshangye-quote-section\" id=\"coreshangye-quote\" aria-labelledby=\"coreshangye-quote-title\">\n<div class=\"coreshangye-quote-grid coreshangye-shell\">\n<div class=\"coreshangye-quote-copy\">\n<h2 id=\"coreshangye-quote-title\">Request Human Milk Oligosaccharide Information<\/h2>\n<p>Tell Sgnutri about your application and requested quantity to discuss an appropriate HMO product, sample availability, and commercial terms.<\/p>\n<ul class=\"coreshangye-quote-list\">\n<li>Telefono: +86-531-69959201<\/li>\n<li>E-mail: sales@sgnutri.com<\/li>\n<li>WhatsApp: +86-186-53457231<\/li>\n<li>Indirizzo: n. 4567, via Xinluo, distretto di Lixia, citt\u00e0 di Jinan, provincia dello Shandong. 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Their identity determines molecular properties, analytical specifications, scientific evidence, and permitted conditions of use. Explore the available Sgnutri product, compare the information needed for formulation, and request documents for your target […]<\/p>","protected":false},"author":30,"featured_media":2295,"comment_status":"open","ping_status":"open","sticky":false,"template":"page-coreshangye.php","format":"standard","meta":{"_acf_changed":false,"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false,"_geo_short_summary":"","_geo_structured_desc":"","_geo_faqs":"","_geo_key_points":"","_geo_target_audience":"","_geo_content_type":"","_geo_last_modified":"","_geo_version":0,"themepark_seo_title":"","themepark_seo_description":"","footnotes":""},"categories":[78],"tags":[],"class_list":["post-49716","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-product-article"],"metadata":{"_wp_page_template":["page-coreshangye.php"],"_thumbnail_id":["2295"],"views":["565"]},"acf":[],"medium_url":"https:\/\/www.sgnutri.com\/wp-content\/uploads\/2025\/01\/pro1-1-300x300.png","thumbnail_url":"https:\/\/www.sgnutri.com\/wp-content\/uploads\/2025\/01\/pro1-1-150x150.png","full_url":"https:\/\/www.sgnutri.com\/wp-content\/uploads\/2025\/01\/pro1-1.png","_links":{"self":[{"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/posts\/49716","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/users\/30"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/comments?post=49716"}],"version-history":[{"count":1,"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/posts\/49716\/revisions"}],"predecessor-version":[{"id":49717,"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/posts\/49716\/revisions\/49717"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/media\/2295"}],"wp:attachment":[{"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/media?parent=49716"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/categories?post=49716"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sgnutri.com\/it\/wp-json\/wp\/v2\/tags?post=49716"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}