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Galacto Oligosaccharide Syrup – Benefits And Applications

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Galacto-oligosaccharide (GOS) syrup is a prebiotic fiber that supports digestive and immune health by stimulating the growth of beneficial gut bacteria, particularly bifidobacteria. Clinical studies, including those published in The Journal of Nutrition and British Journal of Nutrition, have shown that GOS intake can improve stool frequency and modulate immune responses. Produced through enzymatic conversion of lactose using β-galactosidase, GOS syrup is water-soluble, low in calories, and remains stable under heat and acidic conditions. These characteristics make it a common ingredient in infant formulas, functional drinks, and clinical nutrition products aimed at gastrointestinal support.

Galacto oligosaccharide syrup (GOS syrup) is a functional prebiotic derived from lactose through enzymatic transformation, resulting in a mixture of galactose-containing oligosaccharides. Recognized for its health-promoting properties and scientific backing, GOS syrup is frequently used in foods designed to improve gut health and support the intestinal microbiome.

Unlike GOS powder, which comes in a dry, concentrated form, GOS syrup is a liquid formulation that is easier to blend into beverages, infant formulas, and liquid nutritional products. Both forms share similar bioactive benefits, but GOS syrup is preferred in applications requiring easy dispersion and precise dosage control.

This syrup is highly water-soluble, has a low molecular weight, and provides mild sweetness—typically 20% to 40% of the sweetness of sucrose. It is also low in calories, non-digestible, and resistant to heat and acidic environments, making it an ideal ingredient in a variety of functional and shelf-stable formulations.

Galacto Oligosaccharide (GOS) syrup is produced through enzymatic synthesis, where lactose—typically derived from cow’s milk—is converted using β-galactosidase into short-chain galacto-oligosaccharides. This targeted bioconversion ensures a high prebiotic content with minimal monosaccharide residue.

Post-synthesis, the syrup undergoes purification and concentration, using membrane filtration and vacuum evaporation to remove unreacted sugars and achieve the desired GOS concentration (commonly 57%, 70%, or 90%).

Strict quality control protocols ensure the final product meets food-grade or pharmaceutical-grade standards. Parameters such as microbial safety, heavy metals, pH, and moisture content are routinely monitored to ensure consistency, stability, and safety—especially for infant and clinical applications.

Galacto-oligosaccharide (GOS) syrup is widely used in the food and beverage industry due to its prebiotic properties and various health benefits. It is essential to ensure that Galacto-oligosaccharide (GOS) syrup is widely appreciated in the food and beverage industry for its prebiotic benefits. Ensuring the syrup meets quality and safety requirements is crucial. Common specifications include appearance, GOS concentration, moisture levels, pH range, microbial safety, and limits on heavy metals and toxins.

Two common varieties of GOS syrup—GOS 57 and GOS 70—are characterized by specific quality standards. Understanding these specifications helps manufacturers and users maintain consistent product performance across different applications.

ASSAYGOS 57GOS 70
Product NameGalactooligosaccharide SyrupGalactooligosaccharide Syrup
AppearanceColorless or light yellow syrupColorless or light yellow syrup
Dry Matter (%)74.0–76.074.0–76.0
Ash (%)≤0.3≤0.3
Galactooligosaccharides Content (on dry basis, w/%)≥57.0≥70.0
Lactose + Monosaccharide Content (on dry basis, w/%)≤43.0≤30.0
pH2.8–6.02.8–6.0
Arsenic (As), mg/kg≤0.5≤0.5
Lead (Pb), mg/kg≤0.5≤0.5
Total Plate Count, CFU/gn=3, c=0, m=103n=3, c=0, m=103
Total Coliform, CFU/gn=3, c=0, m=10n=3, c=0, m=10
Mold (CFU/g)≤25≤25
Yeast (CFU/g)≤25≤25

These specifications reflect the stringent quality control processes that ensure GOS syrup’s safety and effectiveness in applications ranging from food and beverages to dietary supplements. Manufacturers are encouraged to carefully assess these properties when sourcing GOS syrup to ensure that the product meets their specific needs and regulatory requirements.

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Thanks to its prebiotic properties, mild sweetness, and low glycemic response, GOS syrup has found a wide range of uses in both mainstream and functional food sectors. It is now commonly added to everything from infant formula to sports nutrition products.

  1. Infant Formula and Baby Food
     GOS syrup is widely incorporated into infant formula and baby food products as it mimics the oligosaccharides naturally present in human milk. It supports the development of beneficial gut bacteria, particularly Bifidobacterium, which is vital for infants’ digestive health and immune function.

  2. Sports Drinks and Functional Beverages
     Due to its ability to promote gut health and maintain a balanced microbiome, GOS syrup is becoming a popular ingredient in sports drinks and functional beverages. These drinks help enhance digestion, boost immunity, and maintain overall well-being, particularly for active individuals.

  3. Yogurts, Fermented Milk, and Flavored Dairy
     GOS syrup serves as an effective prebiotic in dairy products like yogurts and fermented milk. It supports the growth of beneficial probiotics, enhancing the overall health benefits of these products. It also contributes to improved texture and consistency without affecting the flavor.

  4. Sugar-Replacement in Diabetic-Friendly Formulations
    GOS syrup is widely used in dietary supplements and gut-health formulations due to its proven ability to stimulate the growth of beneficial gut microbiota such as Bifidobacteria. According to the 2010 study by Davis et al. published in the Journal of Clinical Gastroenterology, regular intake of GOS can improve bowel function and stool transit time. Furthermore, research led by Vulevic et al. in 2015, published in the British Journal of Nutrition, demonstrated that GOS enhances immune response and may alleviate symptoms associated with constipation and irritable bowel syndrome (IBS).

  5. Supplements and Gut-Health Products
     GOS syrup is commonly used in dietary supplements and gut-health products, thanks to its ability to promote the growth of beneficial gut microbiota. It helps improve digestion, support immunity, and potentially alleviate symptoms of constipation and other digestive disorders

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Galacto-oligosaccharide (GOS) syrup is a versatile functional ingredient widely used in the food industry. It supports gut health by promoting beneficial bacteria growth, helps strengthen the immune system, and aids digestion through its prebiotic effects.

Gut Microbiota Balance – Stimulating Growth of Bifidobacteria and Lactobacilli

One of the primary health benefits of GOS syrup is its ability to stimulate the growth of beneficial gut bacteria, particularly Bifidobacteria and Lactobacilli. These beneficial microorganisms play a crucial role in maintaining a balanced gut microbiota, which is essential for digestive health, nutrient absorption, and overall well-being. By promoting the growth of these bacteria, GOS syrup helps maintain a healthy intestinal environment, improving digestion and overall gut function.

Constipation Relief – Especially for Pregnant Women and the Elderly

GOS syrup has shown significant potential in alleviating constipation, a common concern, especially for pregnant women and the elderly. Due to hormonal changes and the compression of the intestines during pregnancy, women often experience constipation. Similarly, the elderly tend to have slower digestion due to a decline in gut flora. GOS syrup promotes regular bowel movements by supporting the growth of beneficial gut bacteria and improving overall intestinal motility.

Immune Support – By Improving the Gut Environment

A healthy gut microbiome is closely linked to a well-functioning immune system. GOS syrup contributes to immune support by creating a favorable environment for beneficial bacteria. This enhances the body’s defense mechanisms against infections and diseases. By maintaining a healthy balance of gut microbiota, GOS syrup helps modulate the immune response, improving overall immune health.

Weight Management – Low-Calorie and Low Glycemic Index Support

As a low-calorie, low-glycemic index ingredient, GOS syrup is beneficial for weight management. It provides sweetness and functional benefits without causing spikes in blood sugar levels, making it an excellent choice for people looking to control their calorie intake. By substituting traditional sugars with GOS syrup, individuals can enjoy food and beverages with fewer calories while still supporting their metabolism and weight goals.

Pediatric Use – Supports Microbiome Development in Children

GOS syrup is particularly valuable in pediatric nutrition, where it supports the development of a healthy microbiome in children. During early life, the gut flora is still developing, and supplementing with GOS can foster a balance of beneficial bacteria like Bifidobacteria, which are essential for children’s immune system development and overall health. GOS syrup is commonly added to infant formula to support these crucial stages of microbiome development.

Compliance with FDA, EFSA, and Codex guidelines
 GOS syrup meets standards set by FDA, EFSA, and Codex Alimentarius.

Kosher/Halal and clean-label certification info
 Many GOS products are Kosher and Halal certified, and clean-label certified for transparency and purity.

Warnings for People with Lactose Sensitivity

Although GOS syrup is derived from lactose, the enzymatic conversion process transforms lactose into oligosaccharides. These oligosaccharides are generally well-tolerated, even by those with lactose sensitivity. However, if you have severe lactose intolerance, I strongly suggest consulting a healthcare provider before using GOS syrup. As an expert, I recommend checking with a healthcare professional if you’re unsure of how your body may react.

Drug Interactions

From my experience, there are no significant, widely recognized interactions between GOS syrup and medications. However, I advise consulting with your healthcare provider if you are on immunosuppressant medications or diuretics. While GOS syrup is beneficial for gut health, it’s always important to ensure that there are no unforeseen interactions with other treatments.

Galacto-Oligosaccharide (GOS) syrup is widely used in food and beverage formulations for its prebiotic benefits, including supporting gut health, immune function, and weight management. With low calories and a low glycemic index, it suits the needs of health-conscious consumers and product developers.

Our GOS syrup meets rigorous quality standards to ensure safety and consistency across various applications, such as infant nutrition, functional beverages, and digestive health products.


Sources / References

·  Davis, L. M. G., Martínez, I., Walter, J., Goin, C., & Hutkins, R. (2010). Fermentability of dietary fibers in vitro and the relationship to gas production, stool weight, and transit time. Journal of Clinical Gastroenterology, 44(4), 293–299.

·  Vulevic, J., Juric, A., Walton, G. E., et al. (2015). Influence of galacto-oligosaccharide on the gut microbiota, immune parameters and metabonomics in elderly persons. British Journal of Nutrition, 114(4), 586–595.

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