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Product details

About The L-Valine

I. Overview

L-Valine is an essential branched-chain amino acid, which means the body cannot synthesize it on its own and must meet its needs through food intake. It plays a key role in many aspects such as metabolism, protein synthesis and maintenance of normal physiological functions of organisms, and is widely used in feed, food, medicine and other fields.

II. Physical and chemical properties

Appearance and properties: Usually in the form of white crystals or crystalline powder, this form facilitates storage, transportation, and subsequent accurate measurement and addition operations in different application scenarios. For example, in feed production, it can be easily mixed evenly with other raw materials; in the pharmaceutical process, it is also convenient for reasonable compatibility with auxiliary materials, which is beneficial to the preparation of corresponding dosage forms of medicines.

Solubility: It has certain solubility in water and can form a clear and transparent solution, but its solubility is relatively limited and it is slightly soluble. However, in dilute acid or alkali solutions, its solubility will be significantly enhanced and it can better participate in chemical reactions or perform corresponding functions. In terms of organic solvents, L-valine has poor solubility in common organic solvents such as ethanol. This solubility characteristic determines that it is mostly used in aqueous solution systems in practical applications, such as in some applications that need to be dissolved. The solubility characteristics in different solvents must be considered when preparing products for subsequent use.

Stability: L-valine is relatively stable under normal temperature, dry and suitable environmental conditions. However, if it is exposed to high temperature, high humidity, strong light or strong oxidants and other adverse environmental factors, its chemical structure may change. Changes occur, resulting in reduced activity or even loss of efficacy. Therefore, attention should be paid to maintaining appropriate environmental conditions during storage and use to ensure its stability.

III. Physiological functions

Participate in protein synthesis: As one of the basic building blocks of protein, L-valine is essential for protein synthesis. According to the instructions of the genetic code, it is connected together with other amino acids in an orderly manner under the action of intracellular structures such as ribosomes to form protein molecules with specific structures and functions. These proteins participate in many physiological processes of the human body, such as the catalysis of biochemical reactions by enzymes, the contraction and relaxation mechanism of muscles, and the immune defense function of antibodies. They are the basis for maintaining normal life activities of the body.

Regulating energy metabolism: L-valine plays an important role in the energy metabolism process, especially in muscle energy metabolism. During exercise or when the body’s energy demand increases, it can be used as an energy substance by muscle tissue and decomposed through specific metabolic pathways to produce energy (in the form of adenosine triphosphate, or ATP) to provide power for activities such as muscle contraction. , it can also regulate the balance of sugar metabolism and fat metabolism in the body, such as affecting insulin sensitivity, which in turn affects glucose uptake and utilization, as well as fat synthesis and decomposition, helping to maintain a healthy state of body energy metabolism and prevent obesity, etc. The occurrence of metabolic diseases.

Maintain normal functions of the nervous system: It has a special nutritional effect on the nervous system, helps maintain the normal structure and function of nerve cells, and ensures the normal conduction of nerve impulses. For example, during the synthesis of neurotransmitters in the brain, L-valine Acid can participate in some of these links, affecting the synthesis and release of neurotransmitters (such as γ-aminobutyric acid, etc.), having a potential impact on regulating mood, sleep and cognitive functions, and maintaining normal physiological activities of the brain and mental function. Health plays a role.

IV. Application areas

Feed industry:

It is a commonly used amino acid additive in animal feed. Since many animals (such as chickens and ducks in poultry, pigs, cows in livestock, etc.) themselves cannot synthesize sufficient amounts of L-valine to meet their growth and development needs, they need to Add extra to your feed. Adding L-valine can improve the nutritional value of animal feed, promote animal growth, enhance the animal’s disease resistance, improve the feed conversion rate, and allow animals to convert the ingested feed into weight gain more efficiently, thus improving breeding efficiency.

Animals of different types and different growth stages have different demands for L-valine. For example, young animals have a relatively higher demand for L-valine during their rapid growth stage. Therefore, when designing feed formulas, it should be based on the specific animal breeds and ages. , feeding environment and other factors to accurately determine the amount of addition to achieve scientific and reasonable nutritional supplementation.

Food industry:

As a nutritional fortifier, L-valine can be added to some specific foods, especially plant protein-based foods, to improve its amino acid composition and make it closer to the ideal amino acid pattern required by the human body, thereby enhancing the food’s nutritional value. The nutritional value can meet the additional needs of different groups of people (such as vegetarians, the elderly, athletes, etc.) for amino acids. For example, adding an appropriate amount of L-valine to some soy products can further improve their nutritional value.

It can also be used in the research and development and production of foods for special medical purposes. For some patients with special health conditions such as abnormal amino acid metabolism or malnutrition, by rationally adding nutrients such as L-valine, we can customize foods that meet their physical needs and assist them. Treat and improve health conditions.

Pharmaceutical industry:

In the medical field, L-valine can be used as an auxiliary treatment for some diseases. For example, for patients with liver disease, appropriate supplementation of L-valine can help improve the metabolic function of the liver, because the liver is an important place for amino acid metabolism. , L-valine participates in various metabolic processes that have positive significance for the recovery of liver function. In addition, in the treatment of certain neurological diseases (such as mood disorders, sleep problems caused by neurotransmitter imbalance, etc.), supplementing L-valine may also be considered to regulate neurotransmitter levels and improve the condition, but the specific Applications need to be carried out under the professional guidance of a doctor.

V. Quality standards and testing

Quality standards:

Different application fields have different emphasis on the quality requirements of L-valine, but generally there are strict limits on its content, impurity content, etc. In the field of feed additives, the content of the active ingredient L-valine is required to reach the specified standard range, and there are corresponding upper limits for heavy metal impurities, moisture content, etc. to ensure that the product meets the requirements for safe and effective use and will not Adverse effects on animal health due to impurities and other issues.

In the pharmaceutical field, the quality standards are even stricter. The purity of raw materials and every aspect of the production process must strictly follow the requirements of Good Manufacturing Practice (GMP) to ensure the quality stability and safety of the product so that it can be used reliably. In terms of disease treatment, etc. In the field of food additives, it is also necessary to comply with corresponding food safety standards to ensure that the added food does not harm the health of consumers.

Detection method:

Commonly used methods to detect L-valine content include high-performance liquid chromatography (HPLC), which can be used to inject the sample into the mobile phase, separate different substances based on the difference in distribution between the stationary phase and the mobile phase, and then detect The instrument detects the peak area and other related parameters of L-valine and compares it with the standard to accurately determine its content.

For the detection of impurity content, such as heavy metal impurities, atomic absorption spectrometry can be used to determine the content of heavy metals by detecting the absorption spectrum of specific metal elements in the sample. This can be used to comprehensively evaluate the quality of L-valine products and determine whether they comply with Corresponding quality standards.

VI. Storage and transportation requirements

Storage conditions:

It should be stored in a cool, dry and well-ventilated environment. It is generally recommended that the storage temperature be below 30℃ and avoid direct sunlight, because high temperature and strong light can easily cause chemical reactions such as decomposition and oxidation, affecting its quality and performance. At the same time, moisture-proof measures must be taken, and packaging containers with good sealing performance can be used to prevent them from absorbing moisture in the air and causing caking, deterioration, etc., and to ensure their stability during storage.

It also needs to be stored separately from oxidants, acids, alkalis and other substances that may undergo chemical reactions to avoid accidents and ensure that storage safety and product quality are not affected.

Shipping requirements:

During transportation, it is also necessary to avoid adverse environmental conditions such as high temperature, sunlight, and rain, and use appropriate packaging materials, such as packaging bags or barrels with moisture-proof, light-proof, and sealed functions, to ensure that the packaging is intact and protected from the outside world. factors destroy its internal chemical structure and quality. Moreover, transportation routes and means of transportation must be reasonably arranged to avoid bumps, collisions and other situations that may cause packaging damage, so as to ensure that the products are transported safely and completely to the destination.

VII. Precautions for use

Dosage: Whether in feed addition, food fortification or pharmaceutical applications, the dosage needs to be strictly controlled. In the feed industry, the amount of addition must be determined scientifically and rationally based on factors such as the type, growth stage, and feeding environment of the animal. Excessive addition may cause adverse reactions such as digestive problems in animals; in food applications, use must be in accordance with relevant food safety standards. Add in a limited amount to avoid excessive addition that affects food quality and consumer health; in the medical field, the doctor’s instructions must be strictly followed to determine the dosage. The doctor will comprehensively consider the patient’s age, illness, physical condition and other factors to accurately give the appropriate dosage. dosage to prevent adverse reactions caused by improper dosage.

Incompatibility: When adding L-valine to feed, pay attention to its interaction with other feed additives. For example, when it coexists with some minerals (such as calcium, iron, etc.), it may affect the dissolution of each other. properties or stability, so it is necessary to ensure the nutritional balance of the overall feed and the compatibility of each ingredient through scientific formula design. In pharmaceutical applications, if other drugs are taken at the same time, drug interactions may occur, and the doctor needs to be informed that L-valine is being used so that reasonable medication adjustment and monitoring can be carried out