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Product details

About The Sodium Ascorbate

I. Overview

Sodium ascorbate is a sodium salt form of ascorbic acid (vitamin C). It has the basic physiological activity of vitamin C. At the same time, due to the characteristics of sodium salt, it has unique performance in solubility and other aspects. It is a compound widely used in many fields such as medicine and food, and plays an important role in maintaining human health and ensuring product quality.

2. Physical and chemical properties

Appearance and properties: It usually appears as a white to slightly yellowish white crystalline powder. This powdery appearance makes it easy to accurately measure, mix and add in different scenarios such as pharmaceutical and food processing. For example, it can be dispersed more evenly in the production of pharmaceutical tablets or when added to food.

Solubility: It has good water solubility and can dissolve quickly and fully in water to form a clear and transparent solution. Its aqueous solution is relatively stable under certain conditions. However, its solubility in organic solvents is poor. This solubility characteristic determines that its use in the preparation of different dosage forms and application scenarios mainly revolves around the aqueous solution system. For example, when making a directly drinkable vitamin C supplement solution, its advantage of good water solubility is fully utilized.

Stability: Compared with pure ascorbic acid, the chemical stability of sodium ascorbate is improved, especially in neutral and weak alkaline environments. However, in strong acidic environments, high temperatures, and long-term exposure to air, chemical reactions such as oxidation may still occur, resulting in reduced activity or failure. Therefore, corresponding protective measures need to be taken during storage and use to maintain its stability.

3. Physiological function

Antioxidant effect: Like vitamin C, sodium ascorbate has a strong antioxidant capacity. It can remove free radicals in the body. Free radicals are a class of unstable molecules or atoms with unpaired electrons. They will attack various biological macromolecules in cells (such as DNA, proteins, lipids, etc.), trigger oxidative stress reactions, and then destroy cell structure and affect cell function, leading to a variety of health problems such as aging, inflammation, and cardiovascular disease. Sodium ascorbate reduces free radicals by being oxidized itself, thereby protecting cells from free radical damage, maintaining the normal structure and function of cells, and playing a positive protective role in human health.

Participate in collagen synthesis: Collagen is an extremely important structural protein in the human body. It is widely present in tissues such as skin, bones, tendons, and blood vessels. It plays a key role in maintaining the strength, elasticity, and normal morphology of these tissues. Sodium ascorbate participates in the hydroxylation reaction during collagen synthesis, which helps to ensure the normal synthesis of collagen, keep the skin firm and elastic, promote healthy bone growth and wound healing, etc. For example, it can help reduce the formation of skin wrinkles and speed up the healing of wounds after surgery.

Enhance immunity: It can affect the function of immune cells (such as white blood cells), stimulate the activity of immune cells, promote the proliferation and differentiation of immune cells, help the human body better identify and resist the invasion of external pathogens (such as bacteria, viruses, etc.), maintain the normal function of the immune system, and play a certain auxiliary role in preventing diseases and recovering from diseases. For example, in the cold season, appropriate supplementation of preparations containing sodium ascorbate can help reduce the risk of infection or alleviate cold symptoms.

Promote iron absorption: In the human intestine, sodium ascorbate can reduce the insoluble trivalent iron to more easily absorbed divalent iron, thereby increasing the absorption rate of iron, which has positive significance for the prevention and treatment of iron deficiency anemia, especially for some vegetarians, pregnant women, the elderly and other high-risk groups of iron deficiency anemia. Intake of sodium ascorbate can better utilize the iron in food and improve anemia.

4. Application fields

Medical field:

It is often used to make vitamin C supplements to prevent and treat diseases such as scurvy caused by vitamin C deficiency. It is also used in the auxiliary treatment of some diseases (such as infectious diseases, trauma repair, etc.). By exerting its antioxidant and immune-enhancing functions, it helps patients improve their physical condition and accelerate the recovery process. For example, in the treatment of burn patients, supplementing sodium ascorbate helps promote the repair of burn wound skin.

It can also be used as an antioxidant in pharmaceutical preparations to prevent the active ingredients in the drugs from becoming ineffective due to oxidation, extend the shelf life of the drugs, improve the stability of the drugs, and ensure the quality and efficacy of the drugs during storage and use. For example, sodium ascorbate will be added in appropriate amounts to some easily oxidized injections, oral liquids and other preparations.

Food industry:

It is a commonly used food nutrient enhancer, which is widely added to various foods, such as beverages, juices, canned foods, cakes, etc., to supplement the content of vitamin C in foods and meet consumers’ demand for nutritional intake. At the same time, it can also improve the quality of food to a certain extent. For example, adding sodium ascorbate to juice can prevent the juice from oxidizing and discoloring, maintain its good color and flavor, and extend the shelf life of the product.

As an antioxidant, it can inhibit oxidation reactions in food, reduce the occurrence of phenomena such as oil oxidation rancidity and pigment fading, protect the nutritional components and sensory quality of food, improve the overall quality of food, keep food in a better state during storage and sales, and extend its edible period.

Cosmetics:

Due to its antioxidant and collagen synthesis-promoting effects, sodium ascorbate is used in some skin care products, such as creams and essences, which helps protect skin cells from free radical damage, delay skin aging, reduce the appearance of skin problems such as wrinkles and spots, keep the skin young and healthy, and enhance the efficacy of skin care products. It is favored by many beauty lovers.

V. Quality standards and testing

Quality standards:

In different application fields such as medicine and food, there are strict requirements for the quality of sodium ascorbate, mainly reflected in content, purity, impurity content, etc. For example, in the field of food additives, the content of its active ingredient (sodium ascorbate) must meet the prescribed standard range, and there are strict limit regulations for heavy metal impurities (such as lead, mercury, etc.) and arsenic content, etc., to ensure that the product meets food safety standards and will not have adverse effects on human health due to impurities and other problems.

In the field of medicine, its quality standards are more stringent. Every link from raw material procurement to production and processing must follow the Good Manufacturing Practice (GMP) of pharmaceutical production to ensure the high purity, high stability and safety of the product, so that the drug can reliably play its related functions such as treatment.

Detection method:

The commonly used methods for detecting the content of sodium ascorbate include iodine titration, which uses the principle of redox reaction between sodium ascorbate and iodine. The sample is titrated with a standard iodine solution of known concentration, and the content of sodium ascorbate in the sample is calculated according to the amount of iodine consumed at the titration endpoint. The operation is relatively simple and accurate.

For the detection of impurity content, such as heavy metal impurities, atomic absorption spectrometry can be used to determine the content of heavy metals by detecting the absorption spectrum of specific metal elements in the sample; arsenic content detection usually uses arsenic spot method or atomic fluorescence spectrometry, etc., and these detection methods are used in combination to comprehensively evaluate the quality of sodium ascorbate products and determine whether they meet the corresponding quality standards.

VI. Storage and transportation requirements

Storage conditions:

It should be stored in a cool, dry and well-ventilated environment. It is generally recommended that the storage temperature be below 20℃ and avoid direct sunlight, because high temperature and strong light can easily cause chemical reactions such as oxidation and decomposition, reducing its activity and quality. At the same time, moisture-proof measures should be taken. Packaging containers with good sealing performance can be used to prevent it from absorbing moisture in the air and causing agglomeration, deterioration, etc., to ensure its stability during storage. It is also necessary to store it separately from substances that may react chemically, such as oxidants, strong acids, and strong alkalis, to avoid accidents and ensure that the safety of storage and product quality are not affected. Transportation requirements: During transportation, it is also necessary to avoid adverse environmental conditions such as high temperature, sun exposure, and rain. Use appropriate packaging materials, such as packaging bags or packaging barrels with moisture-proof, light-proof, and sealing functions, to ensure that the packaging is intact and prevent external factors from destroying its internal chemical structure and quality. In addition, the transportation route and transportation tools should be arranged reasonably to avoid bumps, collisions, and other situations that may cause packaging damage, and ensure that the product is transported safely and intact to the destination. Seven, precautions for use Dosage: In medical applications, the dosage must strictly follow the doctor’s instructions. The doctor will determine the appropriate dosage based on the patient’s age, condition, physical condition, and other factors to prevent adverse reactions caused by improper dosage. For example, excessive use may cause diarrhea, urinary system stones, and other problems. In terms of food additives, it is also necessary to add it in accordance with the usage limits specified in the relevant food safety standards to avoid excessive addition that affects food quality and consumer health.

Incompatibility taboos: In the medical field, sodium ascorbate may interact with some drugs when used at the same time, affecting the efficacy of the drug or increasing the risk of adverse reactions. For example, when it is used at the same time as anticoagulants (such as warfarin), it may enhance the effect of the anticoagulant and increase the risk of bleeding. Therefore, if you are taking other drugs, be sure to inform your doctor so that reasonable medication adjustments and monitoring can be made. In food processing, it is also necessary to consider whether there is any interaction between it and other food additives to ensure that the overall food formula is scientific and reasonable and to ensure the safety and quality of the food.