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Product details

About The Vitamin K3 MNB 96

I. Overview

Vitamin K3 MNB 96, where “MNB” refers to menadione nicotinamide bisulfite, which is also an important form of vitamin K3, and “96” represents its content specification, which means that the content of nicotinamide bisulfite in this substance reaches 96%, showing a high purity, which enables it to perform its corresponding functions more accurately and effectively in various application scenarios.

II. Physical and chemical properties

·Appearance and properties: It usually appears as a white or off-white crystalline powder. This powder state is convenient for operation in multiple links such as production, storage and subsequent addition and use. It is easy to accurately measure and evenly mix. For example, it is convenient to be compatible with other excipients in the pharmaceutical process, or it can be evenly dispersed in the feed raw materials when added to the feed.

·Solubility: It has a certain solubility in water, and its solubility will be affected by external factors. For example, when the temperature rises, the solubility will generally increase, and it can also show specific solubility characteristics in some organic solvents. This solubility characteristic determines its preparation method and convenience of use in different application scenarios. For example, when preparing drug solution dosage forms, it is necessary to consider its solubility in the corresponding solvent to optimize the process.

·Stability: It is relatively stable under suitable storage conditions, but it is sensitive to environmental factors. For example, if it is exposed to strong light, high temperature, and high humidity for a long time, its chemical structure is prone to change, resulting in loss of activity or deterioration, so proper storage is critical to maintaining its quality and performance.

III. Scope of application

·Medical field:

·It is mainly used to treat and prevent various diseases caused by vitamin K deficiency, especially for problems with coagulation function. It can participate in the synthesis of coagulation factors II, VII, IX, and X in the liver, promote the normal production of these coagulation factors, and ensure that the coagulation mechanism of the human body can be effectively activated when bleeding due to injury, and quickly stop bleeding. For example, for some patients with liver diseases that lead to blocked synthesis of coagulation factors, or patients who have long-term and large-scale use of antibiotics that cause intestinal flora disorders and affect the natural synthesis of vitamin K, the use of vitamin K3 MNB 96 for supplementation can help restore normal coagulation function and reduce the risk of bleeding.

· It also has a potential role in some bone health-related therapeutic applications. It can promote the carboxylation of osteocalcin, help calcium to be better deposited in the bones, and enhance bone density and strength. For the elderly, postmenopausal women and other people with a high incidence of osteoporosis, the rational use of vitamin K3 MNB 96 in specific treatment plans may help improve bone health and assist in preventing and alleviating osteoporosis symptoms.

· Animal nutrition field:

· It is a commonly used vitamin additive in animal feed. Given that most animals have a weak ability to synthesize vitamin K on their own, by adding vitamin K3 MNB 96 to feed, it can ensure that animals take in enough vitamin K, maintain their normal coagulation function, avoid various bleeding diseases such as nose bleeding, gum bleeding, and subcutaneous bleeding, and ensure the healthy growth of animals. For example, in poultry farming, adding an appropriate amount of this substance to the feed of chickens, ducks and other poultry can improve the disease resistance and growth performance of poultry, reduce health problems caused by vitamin K deficiency, and improve farming efficiency.

· Animals of different types and different growth stages have different requirements for vitamin K. Therefore, when adding vitamin K3 MNB 96 to the feed formula, it is necessary to accurately determine the amount of addition based on the specific animal (such as pigs, cattle, sheep and other livestock and various poultry) type, age, reproductive status and other factors to achieve scientific and reasonable nutritional supplements and meet the needs of animal growth and health.

IV. Quality Control and Testing

· Quality Standards:

· To strictly comply with relevant national or international quality standards, first of all, in terms of content, it is necessary to ensure that the actual content is close to or reaches the marked 96% level, and the allowable error range is also strictly limited to ensure the consistency and effectiveness of the product. At the same time, there is strict control over the impurity content, and the impurity level should be reduced as much as possible to prevent impurities from having adverse effects on the use of the product or bringing potential safety hazards, such as limiting the content of heavy metal impurities.

·There are also corresponding standards and specifications for physical and chemical properties such as appearance, particle size, and solubility. Only when the product fully meets these standards and requirements can it be legally circulated in the market and applied in the corresponding fields.

·Detection method:

·The commonly used method for detecting its content includes high performance liquid chromatography (HPLC), which can accurately separate and detect the content of vitamin K3 MNB 96 in the sample. By injecting the sample into the mobile phase, the sample is separated based on the distribution difference between different substances in the stationary phase and the mobile phase, and then the peak area and other relevant parameters of the standard are compared to accurately determine its actual content.

·In addition, various detection methods such as atomic absorption spectroscopy to detect the content of heavy metal impurities (for controlling the impurity level) and laser particle size analysis to determine the particle size distribution will be used to comprehensively consider the various quality indicators of the product to ensure that the product quality is reliable and safe to use.

V. Storage and transportation requirements

·Storage conditions:

·It should be stored in a cool, dry and well-ventilated environment. The ideal storage temperature is generally recommended to be controlled below 25℃ and avoid direct sunlight, because high temperature and strong light can easily cause it to undergo chemical reactions such as decomposition and oxidation, thereby reducing its activity and quality. At the same time, moisture-proof work should be done well. Packaging containers with good sealing performance can be used to prevent it from absorbing moisture in the air and causing agglomeration, deterioration, etc., to ensure its stability and effectiveness during storage.

· It is also necessary to place it in a special storage area in accordance with regulations, away from other substances that may produce chemical reactions and dangerous factors such as fire sources, to avoid accidents that affect its quality and safety.

· Transportation requirements:

· During transportation, attention should also be paid to avoid adverse environmental conditions such as high temperature, sun exposure, and rain. Suitable packaging materials, such as packaging bags or packaging barrels with moisture-proof, light-proof, and sealing functions, should be used to ensure that the packaging is intact and prevent external factors from damaging its internal chemical structure and quality. In addition, the transportation route and transportation tools should be arranged reasonably to avoid bumps, collisions, and other situations that may cause packaging damage, and ensure that the product is transported safely and intact to the destination.