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Product details

About The Calcium Ascorbate

I. Overview

Calcium ascorbate is the calcium salt form of ascorbic acid (vitamin C). It combines the physiological activity of vitamin C with the nutritional function of calcium. It has important applications in many fields such as food, medicine and health products. It is a multifunctional compound that can supplement both vitamin C and calcium.

II. Physical and chemical properties

Appearance and properties: It usually appears as a white to slightly yellow crystalline powder. This powder form is convenient for accurate measurement, mixing and addition in the production process of various products. For example, it can be easily mixed with other excipients to form tablets, capsules and other dosage forms in the pharmaceutical process, or evenly integrated into food raw materials in food processing.

Solubility: It has good solubility in water and can dissolve quickly to form a clear and transparent solution. However, compared with some other vitamin C salts, its solubility may be slightly weaker, but it can still meet the use requirements in most application scenarios. In organic solvents, calcium ascorbate has poor solubility, and its application mainly revolves around aqueous solution systems. For example, its water solubility is used for preparation when making oral solution dosage forms.

Stability: Calcium ascorbate has relatively good chemical stability, especially under neutral and weak alkaline conditions. Compared with ordinary ascorbic acid (vitamin C), it is less likely to be oxidized and can maintain its activity for a long time. However, under the influence of adverse environmental factors such as strong acid, high temperature and long-term exposure to air, a certain degree of chemical changes will still occur, resulting in reduced activity. Therefore, it is also necessary to pay attention to the maintenance of appropriate environmental conditions during storage and use.

III. Physiological function

Antioxidant and immunomodulatory effects:

Inheriting the powerful antioxidant properties of ascorbic acid, calcium ascorbate can remove free radicals in the body. Free radicals are highly oxidizing and can damage biological macromolecules (such as DNA, proteins, lipids, etc.) in cells, triggering oxidative stress reactions, thereby affecting the normal function of cells and causing various health problems in the body. Calcium ascorbate reduces free radicals by being oxidized itself, protects cells from free radicals, maintains the integrity of cell structure and function, and has positive significance in delaying aging and preventing cardiovascular diseases.

At the same time, it also plays a regulatory role in the immune system, can enhance the activity of immune cells (such as white blood cells), promote the proliferation and differentiation of immune cells, help the human body better identify and resist the invasion of external pathogens (such as bacteria, viruses, etc.), maintain the body’s immune function in good condition, and play a certain auxiliary role in disease prevention and disease recovery. For example, in the cold season, appropriate supplementation of preparations containing calcium ascorbate can help enhance the body’s resistance, reduce the risk of infection or alleviate cold symptoms.

Participate in collagen synthesis: Like ordinary ascorbic acid, calcium ascorbate participates in the hydroxylation reaction during collagen synthesis. Collagen is widely present in human skin, bones, tendons, blood vessels and other tissues, and plays a key role in maintaining the structure, strength and elasticity of these tissues. Calcium ascorbate helps ensure the normal synthesis of collagen, makes the skin firmer and more elastic, promotes healthy bone growth and wound healing, such as helping to reduce the formation of skin wrinkles and speed up the healing of wounds after surgical operations.

Calcium supplementation function: As a calcium salt, it can provide the human body with absorbable calcium. Calcium plays a vital role in the normal development and health maintenance of human bones and teeth, especially for the bone growth of children and adolescents, and the prevention of osteoporosis in the middle-aged and elderly. At the same time, calcium is also involved in many physiological processes of the human body, such as muscle contraction and nerve conduction. While supplementing vitamin C, calcium ascorbate also provides the necessary calcium source for these physiological activities.

IV. Application fields

Food industry:

It is often used as a food nutrition enhancer and added to various foods, such as beverages, dairy products, cakes, health foods, etc. It can not only supplement the content of vitamin C in food and meet consumers’ demand for nutritional intake, but also increase the supply of calcium and enhance the nutritional value of food. For example, adding calcium ascorbate to some children’s nutritional drinks can supplement vitamin C and calcium for children at the same time, which helps children grow healthily.

It is also an effective antioxidant that can inhibit oxidation reactions in food, prevent food from changing color, taste, oil oxidation and rancidity, extend the shelf life of food, and maintain good sensory quality and nutritional value of food. For example, adding an appropriate amount of calcium ascorbate to edible oil can delay oil oxidation and maintain the quality of edible oil.

Medical field:

It can be used to prevent and treat diseases such as scurvy caused by vitamin C deficiency. At the same time, given its multiple functions such as antioxidant, immunomodulatory and calcium supplementation, it is also used in the auxiliary treatment of some diseases (such as infectious diseases, trauma repair, osteoporosis, etc.). For example, in the treatment of osteoporosis patients, calcium ascorbate can not only supplement calcium, but also promote bone health by participating in collagen synthesis, playing an auxiliary therapeutic role.

In pharmaceutical preparations, calcium ascorbate is sometimes used as an antioxidant to prevent the active ingredients in the drug from being oxidized and becoming ineffective, and to ensure the stability and efficacy of the drug during storage and use. For example, calcium ascorbate is added in appropriate amounts to some easily oxidizable injections, oral liquids and other preparations.

Health care products: There are many health care products on the market with calcium ascorbate as the main ingredient, mainly for those who want to supplement vitamin C and calcium at the same time, such as middle-aged and elderly people, vegetarians, etc. These people often have a high demand for these two nutrients. Health care products made of calcium ascorbate exist in a variety of dosage forms such as capsules, tablets, powders, etc., which are convenient for different consumers to choose according to their preferences and taking habits.

V. Quality standards and testing

Quality standards:

Different application fields have different emphasis on the quality requirements of calcium ascorbate, but generally have strict regulations on its content, purity, impurity content, etc. In the field of food additives, the content of its active ingredient (calcium ascorbate) must meet the specified standard range, and there are strict limit regulations on heavy metal impurities (such as lead, mercury, etc.) and arsenic content to ensure that the product meets food safety standards and will not have adverse effects on human health due to impurities and other problems.

In the pharmaceutical field, its quality standards are more stringent. Every link from raw material procurement to production and processing must strictly follow the Good Manufacturing Practice (GMP) to ensure that the product has high purity, high stability and safety, so that it can reliably play related functions such as treatment.

Detection method:

The commonly used method for detecting the content of calcium ascorbate is titration. For example, by using the principle of redox reaction with specific reagents, the sample is titrated with a standard solution of known concentration, and the content of calcium ascorbate in the sample is calculated according to the amount of standard solution consumed at the titration end point. This method is relatively simple to operate and has high accuracy.

For the detection of impurity content, such as heavy metal impurities, atomic absorption spectroscopy can be used to determine the content of heavy metals by detecting the absorption spectrum of specific metal elements in the sample; arsenic content detection usually uses arsenic spot method or atomic fluorescence spectroscopy, etc., and uses a variety of detection methods to comprehensively evaluate the quality of calcium ascorbate products and determine whether they meet the corresponding quality standards.

VI. Storage and transportation requirements

Storage conditions:

It should be stored in a cool, dry and well-ventilated environment. The ideal storage temperature is generally recommended to be controlled below 20℃ and avoid direct sunlight, because high temperature and strong light can easily cause chemical reactions such as oxidation and decomposition, reducing its activity and quality. At the same time, moisture-proof measures should be taken, and packaging containers with good sealing performance should be used to prevent it from absorbing moisture in the air and causing agglomeration and deterioration, so as to ensure its stability during storage.

It should also be stored separately from oxidants, strong acids, strong alkalis and other substances that may react chemically to avoid accidents, ensure the safety of storage and the quality of the product.

Transportation requirements:

During transportation, it is also necessary to avoid adverse environmental conditions such as high temperature, sun exposure and rain, and select suitable packaging materials, such as packaging bags or packaging barrels with moisture-proof, light-proof and sealing functions, to ensure that the packaging is intact and prevent external factors from damaging its internal chemical structure and quality. In addition, the transportation route and transportation tools should be arranged reasonably to avoid bumps, collisions and other situations that may cause packaging damage, and ensure that the product is transported safely and intact to the destination.

VII. Precautions for use

Dosage: In medical applications, the dosage must be determined strictly in accordance with the doctor’s instructions. The doctor will comprehensively consider the patient’s age, condition, physical condition and other factors to accurately give the appropriate dosage to prevent adverse reactions caused by improper dosage. For example, excessive use may cause gastrointestinal discomfort, hypercalcemia and other problems. In terms of food additives, it is also necessary to follow the use limits specified in relevant food safety standards to avoid excessive additions that affect food quality and consumer health.

Contraindications: In the medical field, calcium ascorbate may interact with some drugs when used at the same time, affecting the efficacy or increasing the risk of adverse reactions. For example, when it is used at the same time as anticoagulants (such as warfarin), it may enhance the effect of anticoagulants and increase the risk of bleeding. Therefore, if you are taking other drugs, be sure to inform your doctor so that reasonable medication adjustments and monitoring can be made. In food processing, it is also necessary to pay attention to whether there is any interaction between it and other food additives to ensure that the overall food formula is scientific and reasonable and to ensure the safety and quality of the food.